The Hoverer Queen is a boss in Sanctum 2.
The Hoverer Queen is simply an upgraded Hoverer. It is the only boss that does not destroy towers with its attack. Its shockwave attack has a larger area of effect and knockback than the regular Hoverer.
Targetting the weakspot on the Hoverer Queen's back from range is the fastest way to kill it. Alternately, using a Drone tower, the Drone Launcher weapon, or jumping behind it with a fully charged Shotgun can be effective as well.